Abstract
In this paper, we report a microfluidic device for pairing uniformly sized liposomes and fusing the paired liposomes. Our microfluidic device is composed of dynamic micro array for pairing liposomes and three-dimensional electrode for fusing liposomes. Electrodes should be located in proper position of a dynamic micro array for applying sufficient electric field to fuse liposomes. By using low melting point alloy, 3D electrodes were integrated in the dynamic microarray device to fuse the paired liposomes. Two uniformly sized liposomes were successfully paired in the dynamic micro array device and fused by the integrated 3D electrode. We believe that this dynamic micro array device will become a useful microfluidics device for vesicle fusion.
