Investigation for prevalence of drug-resistant bacteria at departments for the patients with severe motor and intellectual disabilities, neuromuscular diseases.

Abstract

In recent years, the increase in antibiotic-resistant bacteria of H. influenzae, S. pneumoniae become the remedial problem. We investigated antibiotic-resistant situation for H. influenzae, S. pneumoniae isolated from the patients’ sputum who have the neuromuscular disease, which were gathered in our hospital during a period from April, 2010 to March, 2013. The frequency of isolation of β-lactamase non-producing ampicillin resistant (BLNAR) was found to be 48% in whole H. influenzae. The frequency of isolation of penicillin- resistant S. pneumoniae (PRSP) was found to be 52% in whole S. pneumoniae. In the patients who underwent the tracheal separation and patients with severe motor and intellectual disabilities (SMID), BLNAR and PRSP strains were tend to be isolated more than the others. The number of isolation of the PRSP/PISP was significantly higher than PSSP in S. pneumoniae isolated from SMID. The appropriate usage of antibiotics and vaccines is needed to prevent the antibiotics resistance and to protect from serious infection.