Abstract
A prospective observational study was conducted for examining the effect and adverse events of polyethylene glycol preparation (PEG; MOVICOL®) for patients with severe motor and intellectual disabilities (SMID) who have intractable chronic constipation. By administration of PEG, the number of spontaneous defecation was significantly increased (p= 0.04), and the number of usage of cure medicines (e.g. glycerin enema) was decreased (p= 0.03). Stool hardness did not differ before and after PEG administration. No significant adverse events were observed. PEG can be a new treatment option for patients with SMID who do not respond to conventional therapies for constipation.
