Abstract
Osteoporosis is such a desease that the bone volume decreases with aging. As the mechanism of osteoporosis, the following is accepted widely: the bone resorption exceeds relatively the bone formation owing to a decrease in bone metabolic activity. In the past, the present authors have analyzed theoretically the progressive rate of the osteoporosis generated in a cancellous bone, and have clarified that the dynamic change in bone volume density depends on the remodeling activity of bone as well as the structural characteristic of trabecular architecture.
In order to confirm this theroy, an experimental study was carried out in this paper. Firstly, the real bone volume fraction was measured by using the upper end of the osteoporotic femur dissected from cadavers. Then the result was compared with the theroetical value. As a result, it was learned that the decreasing tendency of the density predicted by the theoretical equation was well in accordance with the actual one.
