2023 Volume 28 Issue 1 Pages 64-
The novel coronavirus disease 2019( COVID-19 )has undergone multiple mutations, and the current dominant strain is the highly infectious omicron mutant strain. The number of pediatric cases have increased, and more cases are displaying convulsions, impaired consciousness, encephalitis, and encephalopathy. Some severe cases may even have sequelae. We present three pediatric COVID-19 cases with acute encephalopathy. Similar to influenza encephalopathy, acute pediatric COVID-19 encephalopathy can display varied clinical presentations, severity, and prognoses.