Neurosurgery for Cognitive Disorder
Online ISSN : 2436-0937
A case of giant malignant meningioma of the anterior skull base with improved cognitive dysfunction after tumor resection
Hirokazu NagasakiRyo NogamiKeita HashimotoMichihisa NarikiyoSo OhashiHidenori MatsuokaYoshifumi Tsuboi
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2024 Volume 4 Issue 1 Pages 9-13

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Abstract

Olfactory groove meningiomas (OGMs) may grow large before symptomatic manifestations. We present the case of a 48-year-old woman with a history of worsening olfactory disturbance, visual impairment, and cognitive dysfunction. Magnetic resonance imaging (MRI) revealed a huge OGM with peritumoral edema. The patient underwent microsurgical resection for total gross tumor removal, and cognitive function improved postoperatively. Progressive cognitive and olfactory dysfunctions and decreased spontaneity in olfactory meningiomas are similar to the early symptoms of Alzheimer's disease and should be considered for differential diagnosis. The problem of patients' refusal to seek medical attention owing to the effects of dementia has been noted. Although symptoms of dementia also appeared in the present case, the patient was eventually taken to the hospital owing to difficulties in caring for her. Refusal to seek medical care delays appropriate medical intervention and may result in missed treatment opportunities. Particularly, OGM removal is expected to improve symptoms. Therefore, making a differential diagnosis and early treatment are crucial.

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© 2024 Japan Society of Neurosurgery for Dementia
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