Vasculitic neuropathy

Abstract

Because most of the vasculitic neuropathy patients require rigorous, long–standing immunosuppressive therapy, the accurate diagnosis, especially based on the pathological detection of vasculitic changes, is the first step of treatment. In this regard, the value of sural nerve biopsy combined with peroneus brevis muscle biopsy is still not ignorable. In the treatment of vascultic neuropathy, there are no controlled treatment trials and clinical practice is guided by experience from case series and indirectly by analogy with systemic vasculitis. Although combined therapy using prednisolone and cyclophosphamide is usually recommended by experts, tailor–made treatment regimen based on the conditions of each patient would produce the best outcome in vasculitic neuropathy. High–grade clinical evidences specialized in the treatment of vasculitic neuropathy are eagerly awaited.