Factors affecting central sensitization

Abstract

Central sensitization is a neurophysiological state in which the central nervous system is overexcited in response to stimuli. It is thought to be associated with painful diseases such as migraine and fibromyalgia, as well as conditions that cause functional physical symptoms. In our study, we found that those with chronic headache had higher central sensitization and higher levels of central sensitization have been shown to reduce quality of life.