2022 Volume 39 Issue 1 Pages 37-41
A 39–years–old woman presented with generalized seizures after 7 days of fever. Generalized seizures did not stop despite administration of several anti–epileptic drugs and sedatives. We diagnosed new–onset refractory status epilepticus (NORSE). Immunotherapy was started from the early stage and thiamylal coma therapy was performed for a few weeks. As seizures declined, we decreased thiamylal sodium and succeeded in stopping use of sedative agents. Tetany–like symptoms were identified in the hands and toes.
The etiology and optimal treatment of NORSE remain unclear, and accumulation of more cases is needed.