Migraine and sleep

Abstract

Migraine is a highly disabling prevalent neurological disease. Cortical spreading depression/depolarization, central sensitization, and neurogenic inflammation in trigemino–vasular system involve the pathophysiology of migraine. Serotonin, dopamine, and calcitonin gene related peptides relate closely these phenomenon.

The relationship between headache disorders and sleep disorders can categorize 1) headaches cause sleep disorders, 2) sleep disorders (disturbances) cause or worse headaches, 3) Somewhat common factor(s) cause both headache and sleep disorders.

In this lecture, I summarized possible relation of migraine and sleep disorders including sleep apnea, somnambulism, restless legs syndrome, narcolepsy.

21st century headache involves new territory and special concern to sleep hygiene are essentially important.