Diagnosis and treatment of autoimmune epilepsy

Abstract

ILAE classification of the epilepsies (2017) has adopted “immune” as one of the etiologies of epilepsy. Autoimmune epilepsy is regarded as a forme fruste of autoimmune encephalitis, where epileptic seizure is the sole or main feature of the disease. I will review the clinical characteristics of autoimmune epilepsy, practical diagnostic algorithm and score (without antibody testing), treatment and underlying autoimmune pathophysiology in this review. The earlier diagnosis and treatment impact the prognosis of this entity.