Abstract
Drug fever is a fever that commonly appears after 7-10 days of drug administration and disappears after discontinuation of the offending agent. Postoperative high fever makes differential diagnosis between drug fever and infection difficult. We report a case of drug fever caused by antibiotics for postoperative infection.
A 40-year-old male underwent surgery for mandibular odontogenic tumor and suffered postoperative infection. Antibiotics were administered, and high fever appeared 8 days after removal of the titanium mesh and plate. As drug fever was suspected, vancomycin and amoxicillin were discontinued, and the fever reduced as a result. Therefore, the fever was diagnosed as drug fever caused by antibiotics.