Abstract
A 55-year-old male with myelodysplastic syndrome had been treated at the Hematology Department at our hospital. Swelling of the left cheek developed in the patient, which led to his referral to our department. Since blisters and distinct dark red plaques were noted on the right forearm as well as the lower limbs, a dermatological examination was requested. Biopsy of the skin rash was performed; the biopsy result and clinical course led to the diagnosis of cheek phlegmon associated with Sweet's disease. We provided treatment for the infection and Sweet's disease. The patient received transfusions of peripheral stem cells. He has had a good outcome for 3 years and 6 months.