Abstract
Angiosarcoma of the breast is rare and the prognosis is poor. There are few reports of intraoral metastasis of breast cancer in Japan, and metastatic tumors of the oral region are rare, representing about 1% of malignant tumors in the oral cavity. We performed oral management on a patient that received chemotherapy for angiosarcoma, and reported diagnosable intraoral multiple metastases during the period. The patient received a medical examination at our department for oral management with chemotherapy in view of pulmonary metastasis and liver metastasis. The cancer metastasized to the rhinopharynx, oropharynx, and the brain, and so chemotherapy was administered. Multiple metastases in the oral cavity were found. We noted a neoplastic change to the right upper jaw, left lower molar and left lower anterior tooth gingiva. We performed an excisional biopsy on the left anterior gingiva tumor. It was pathological, and metastasis of angiosarcoma was diagnosed. A right upper jaw tumor and left lower jaw tumor closely resembled it macroscopically, and a metastatic tumor was thereby clinically diagnosed. She died of multiple organ failure 11 months after our first medical examination.
