セファランチン®の投与によって改善した口腔扁平苔癬の1例

村上 幸生; 香村 亜希子; 岡田 知之; 川田 朗史; 松村 正晃; 丸山 直美; 大井 優一; 田村 靖子; 町野 守; 片山 直

doi:10.15214/jsodom.30.28

Clinical Reports

A Case of Oral Lichen Planus Improved by Administration of Cepharanthin

YUKIO MURAKAMI, AKIKO KOMURA, TOMOYUKI OKADA, AKIFUMI KAWATA, MASAAKI MATSUMURA, NAOMI MARUYAMA, YUICHI OI, SEIKO TAMURA, MAMORU MACHINO, TADASHI KATAYAMA

Author information

YUKIO MURAKAMI
Division of Oral Diagnosis and General Dentistry, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry
AKIKO KOMURA
Division of Oral Diagnosis and General Dentistry, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry
TOMOYUKI OKADA
Division of Oral Diagnosis and General Dentistry, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry
AKIFUMI KAWATA
Division of Oral Diagnosis and General Dentistry, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry
MASAAKI MATSUMURA
Division of Oral Diagnosis and General Dentistry, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry
NAOMI MARUYAMA
Division of Oral Diagnosis and General Dentistry, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry
YUICHI OI
Division of Oral Diagnosis and General Dentistry, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry
SEIKO TAMURA
Division of Oral Diagnosis and General Dentistry, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry
MAMORU MACHINO
Division of Oral Diagnosis and General Dentistry, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry
TADASHI KATAYAMA
Division of Oral Diagnosis and General Dentistry, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry

Keywords: oral lichen planus, Stephania cepharantha Hayata, cepharanthin

JOURNAL FREE ACCESS

2017 Volume 30 Issue 1 Pages 28-31

DOI https://doi.org/10.15214/jsodom.30.28

Details

Abstract

Oral lichen planus is an intractable chronic inflammatory lesion with dyskeratosis, appearing more commonly on the buccal mucosa. Here we describe a case of oral lichen planus starting on the bilateral buccal mucosa in a 70-year-old female patient that showed great improvement. The patient's condition gradually improved after treatment with cepharanthin, an alkaloid agent extracted from Stephania cepharantha Hayata. A review of some additional literature pertaining to probable mechanisms of action is included.

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