Abstract
Bisphosphonate-related osteonecrosis of the jaw is closely related to actinomycetes infection, and overseas reports have hypothesized that the occurrence of osteomyelitis is due to actinomycete infection in bisphosphonate-induced osteonecrosis.
We encountered a case where osteonecrosis in a patient, who had been administered bisphosphonates, progressed to osteomyelitis of the mandible due to actinomycete infection. Here we report this case and review the related literature. The patient underwent sequestrum removal and the wound was left open. After the surgery, the patient was administered AMPC 750mg/day for 2 months. Bone exposure was not observed 17 months after the surgery.
