Abstract
Multiple endocrine neoplasia （MEN） is a genetic disorder that results in neoplastic lesions in multiple endocrine organs, and is classified into types 1, 2A, and 2B. MEN 1 is an extremely rare disorder that can manifest as 20 or more types of functional and non-functional tumors. In this study, we report a case of buccal mucosal fibrolipoma in a patient with MEN1. The patient was a 52-year-old man whose chief complaint was a mass in the left buccal mucosa. He was being followed up for MEN 1 that had been diagnosed at another hospital. During the initial examination, we observed an 8-mm, soft, elastic, mobile mass in the left buccal mucosa. He was diagnosed with a buccal mucosal tumor, which was then resected under local anesthesia. Histopathological diagnosis revealed that the tumor was a fibrolipoma. Lipomas have been reported as a type of non-functional tumor observed in MEN 1. Lipomas are not rare. However, there have been few reported cases of intraoral mucosal lipomas, and we suspect that the lipoma in this case was a symptom of MEN 1. As of 2 years and 6 months after surgery, no recurrence or new systemic symptoms have been observed.
