Japanese Journal of Oral Diagnosis / Oral Medicine
Online ISSN : 2188-2843
Print ISSN : 0914-9694
ISSN-L : 0914-9694
Clinical Reports
A Case of Adult Langerhans Cell Histiocytosis in the Mandible That Resolved Following Biopsy
TOSHIYUKI AKIMORIDAISUKE UEDAMAYUKO TAKADAKOUSEI KABATATOSHIRO MIYAZONOAKIHIKO MIYAWAKI
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2021 Volume 35 Issue 1 Pages 66-70

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Abstract
Langerhans cell histiocytosis (LCH) is a rare condition that is common in children but rarely occurs in adults. Although the treatment plan for LCH differs according to its clinical form, there are some forms for which no therapy has been established. We report a case of LCH involving the mandible of an adult patient in whom the lesion disappeared after a biopsy specimen was obtained for histopathological examination. A 33-year-old man presented to our department with a chief complaint of pain in the left mandibular molar region. Computed tomography (CT) revealed a translucency at a site continuous with the roots of the tooth. Histopathological examination of the biopsy specimen confirmed LCH. 19 months after the biopsy, CT showed bone formation at the biopsy site. Although there is no established treatment for LCH in the oral and maxillofacial region, it may disappear following surgical manipulation such as biopsy, and spontaneous resolution may be expected during follow-up of the patient after biopsy.
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© 2021 The Japanese Society of Oral Diagnosis / Oral Medicine
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