Abstract
Zinc plays an essential role in humans, including numerous enzymatic catalysis and protein synthesis processes. Although the relationship between dysgeusia and zinc deficiency is widely recognized, there are few reports of stomatitis related to zinc deficiency. While stomatitis has various causes, in many cases the removal of the source of pain or application of steroidal ointment often leads to complete healing within one or two weeks. In certain cases of intractable stomatitis associated with low serum zinc levels, zinc supplementation may lead to complete healing. We experienced five cases of effective zinc supplementation in intractable stomatitis. We recommend the routine screening of zinc serum levels in intractable stomatitis cases.
