Japanese Journal of Oral Diagnosis / Oral Medicine
Online ISSN : 2188-2843
Print ISSN : 0914-9694
ISSN-L : 0914-9694
Clinical Reports
A Case of Ameloblastic Fibro-odontoma under the Old Classification: A Literature Review of Ameloblastic Fibro-odontoma and Related Diseases
HIDEHARU KATOSHIGEAKI YANASEKOJI HORISHINNOSUKE NAKAMURAYOSHIHIKO MATSUMURA
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2025 Volume 38 Issue 2 Pages 74-81

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Abstract
Ameloblastic fibro-odontoma and ameloblastic fibrodentinoma were deleted from the 2017 WHO classification, 4th edition, of odontogenic tumors and were described as developing odontomas. The 2024, 5th edition states that ameloblastic fibro-odontoma and ameloblastic fibrodentinoma are histologically and genetically intermediate between ameloblastic fibroma and odontoma. We encountered a patient with ameloblastic fibro-odontoma under the 2005 WHO classification, 3rd edition. We report the case with a review of the literature in Japanese, with regard to differences among ameloblastic fibro-odontoma, ameloblastic fibrodentinoma, ameloblastic fibroma and odontoma.
The patient was a 9-year-old girl who was brought to our hospital for a chief complaint of swelling of the right cheek. A 50-mm radiolucent lesion with a clear boundary was noted in the right lower molar region over the mandibular ramus and a radiopaque region was present in the lesion. The lesion was enucleated and diagnosed as ameloblastic fibro-odontoma. Seven years after the operation, the clinical course is good, and there is no evidence of recurrence.
In past literature, the characteristics of ameloblastic fibro-odontoma and ameloblastic fibrodentinoma differed from those of ameloblastic fibroma and odontoma. Thus, ameloblastic fibro-odontoma or ameloblastic fibrodentinoma should continue to be clearly described with the current diagnosis for the purpose of future research.
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© 2025 The Japanese Society of Oral Diagnosis / Oral Medicine
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