Abstract
The transition of intelligent systems from laboratories to real world in the last decade has created a need for humanization of intelligent systems. In this paper we outline human-centered framework for development of intelligent systems. A distributed multi-layered multi-agent architecture is one of the four components of the framework. We describe in this paper that how the multi-layered architecture facilitates human-centered modelling of intelligent systems from multiple perspectives. The framework and the distributed multi-layered multi-agent ontology has been applied in a range areas including alarm processing, web mining, image processing, sales recruitment and medical diagnosis.