2000 Volume 13 Issue 2 Pages 367-379
The purpose of this study was to morphologically and histomorphometrically evaluate the osseointegration between regenerated bone and dental implants. Following a four-month healing period after tooth extraction of beagle mandible, e-PTFE membranes were placed over the standardized defects. Subsequently, five different bone-filling materials were randomly placed under the membranes. The materials used were autogenous bone graft, demineralized freeze-dried bone powder of dog origin, bovine inorganic xenograft, beta-tricalcium phosphate, collagen-fleece, and membrane alone as a control. Following a healing period of six months, non-submerged implants with a titanium plasma coated surface were inserted in the sites. Three months after implant placement, the specimens were histologically analyzed in the non-decalcified sections.
On the radiographic measurement of defect sites in the beagle's mandibles at the ridge augmentation, recovery of bone height by GBR in DFDBA, auto-bone and TCP graft sites was much better than in the control, collagen and Bio-Oss® graft sites with statistically significant differences.
No statistically significant differences were revealed in direct bone contact rate between the six groups. The percentages of Bio-Oss® remnants demonstrated higher rates than the other four materials three months after implantation. The results suggested that implants could achieve good bone contact with regenerated bone in defects filled with a variety of bone filling materials.
