Experimental Study on Mandibular Reconstruction with Porous Hydroxyapatite Ceramics

Abstract

We made an experimental study on the mandibular reconstruction with porous hydroxyapatite ceramics(HAP)for the purpose of clinical use. Block type of porous apatite was implanted into an artificial defect of dog mandible and the bone formation was examined histologically.
The following results were obtained:New bone formation was observed around the apatite and in the pores one month after the implantation. Bone formation was, however, stopped when a granulation tissue developed between the apatite and mandibular bone in the early stage. Bone formation around the apatite attached to the periosteum was not observed.Although in the area of alveolar bone active new bone formation was observed, it was poor in the area of cortical bone.