Special Articles: How Has the Basic Research Abroad Changed the Implant Therapy?: From Bench to Clinic
Basic Research for Prevention of Peri-implantitis
2019 Volume 32 Issue 2 Pages 126-132
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2019 Volume 32 Issue 2 Pages 126-132
Many studies have suggested that peri-implantitis causes inflammation similar to periodontal disease due to the accumulation of plaque. Furthermore, the soft tissue around dental implants, with weak connective tissue sealing and epithelial adhesion and low resistance to infection, is different from that of natural teeth. To date, various clinical approaches for peri-implantitis have been reported, but no successful clinical application has been suggested. Under this situation, various basic studies have been conducted to obtain a long-term prognosis for implants, one of which is soft tissue sealing at the implant transmucosal area.
Since 2015, we have been conducting joint research with Harvard University School of Dentistry for the purpose of improving adhesion between titanium and oral epithelium. In our study, we have fixed peptide-conducting epithelial cells to pure titanium polished surfaces treated with PA linker and confirmed strong adhesion of epithelial cells. Through this study, we consider future research of soft tissue sealing.
