Abstract
Neck recurrence after neck dissection is an important problem in the treatment of oral cancer. The neck recurrence rate is estimated at about 10% in radical neck dissection and the prognosis for such patients is extremely poor. Surgical resection of the recurrent lesion in the neck is still an effective method, but surgical treatment is not possible for level II neck recurrence due to anatomical reasons. Recently, selective intra-arterial chemotherapy concurrent with radiotherapy (SIACRT) has become popular in advanced head and neck carcinoma treatment, and some reports described that SIACRT was also very effective for controlling nodal disease, even for bulky nodal ones. In this report, we describe two cases of oral cancer with neck recurrence after neck dissection which were successfully treated by SIACRT using docetaxel-nedaplatin.