A case of superselective intra-arterial infusion chemoradiotherapy for advanced maxillary gingival cancer

Method of double simultaneous catheterization from the superficial temporal artery

Abstract

The administration of chemoradiotherapy for oral cancer by intra-arterial infusion via the superficial temporal artery could lead to excellent anti-tumor effects by introducing the anti-cancer drug at a high concentration.
We report a case of superselective intra-arterial infusion chemoradiotherapy for advanced maxillary gingival cancer using a double simultaneous catheterization method involving the maxillary artery and facial artery via the superficial temporal artery. A male patient aged 60 years old with left maxillary gingival cancer (T3N0M0) was hospitalized. The treatment protocol was as follows: five courses of radiotherapy (total dose 50Gy/25fr/5weeks) and superselective intra-arterial infusion chemotherapy using DOC (total dose: 75mg/m², 15mg/m²/week), CDDP (total dose: 125mg/m², 5mg/m²/day). A complete response was obtained by this therapy. The tumor has not recurred for four years, with no need for surgery. This method showed a high anti-tumor effect against advanced maxillary gingival cancer.