Abstract
Kaposi’s sarcoma (KS) is a malignant tumor and is one of the major complications of patients with AIDS, but is rare in Japan. We report a case of AIDS-associated multiple KS of the oral region on the basis of clinical and pathological findings. The patient was a 32-year-old male who had been suffering from a gingival neoplasm-like mass of the incisor region of the maxilla. Intraoral findings showed multiple lesions in this patient. He was diagnosed with AIDS based on data of HIV-RNA: 180,000 copies/ml and CD4: 27/μl. Therefore, the patient’s oral lesion was suspected to be oral KS. A histopathological examination of a gingival biopsy specimen showed typical findings of KS. Furthermore, we confirmed the presence of human herpesvirus (HHV)-8 in this case by immunohistochemistry. Combination anti-retroviral therapy (ART) and liposomal doxorubicin was administered and the patient achieved complete remission (CR) for 3 years.
