Abstract
Basal cell adenocarcinoma （BCAC） comprises approximately 2％ of malignant salivary gland tumors, of which more than 90％ occur in major salivary glands such as the parotid gland; those in the minor salivary glands are extremely rare. Here, we report a single case of basal cell adenocarcinoma originating in the soft palate and discuss and review the relevant literature.
A 65-year-old woman presented with a 12×10mm elastic slightly hard tumor in her left soft palate. The tumor was resected under general anesthesia. The resected tumor was spherical, elastic slightly hard, and covered by a thin capsule. Sectioning revealed a solid interior. A rapid intraoperative histopathological examination indicated monomorphic adenoma. Further histopathological examination of the resected specimen showed a tumor covered by a fibrous capsule formed by basal cell-like cells with an alveolar and papillary growth pattern and partial palisade arrangements at the alveolar margins. The tumor cell nuclei were oval shaped with minimal dyskaryosis, but infiltration and blood vessel invasion into the tumor capsule was observed. In addition, 4 mitotic images were observed in 10 enlarged magnifications, and Ki-67 LI was ＞10％. Based on these findings, the histopathological diagnosis was BCAC. Currently, progress is good and the patient is free of the disease.
