Abstract
Clinical research begins with a “question” in daily clinical practice. In order to solve and verify these questions, clinical research is conducted. This paper describes an outline and the practice of clinical research. Doctors, dentists, and others engaged in medical care are “scientists”. Those who do science are true “medical practitioners”. Desk studies are important in science, but without practice, one is not a medical scientist. We need to acquire knowledge, apply the knowledge to practice, and experience a lot in clinical practice. From this experience, we can identify problems and then try to solve them. This process is called “clinical research”. The results are then generalized and make a significant contribution to medicine. It is important to read a lot of literature, eagerly do clinical practice, observe and identify well, think deeply, and work hard on clinical research.