A case of recurrent adult T-cell leukemia/lymphoma in the mandible

Abstract

T-cell lymphomas that participate in human T-cell leukemia virus type I (HTLV-I) are called adult T-cell leukemia/lymphoma (ATL/L) . A case of tumor-forming ATL/L in the mandible after treatment of adult T-cell leukemia (ATL) is reported herein.
A 69-year-old male visited our department with a complaint of swelling on the left mandible. The patient had underwent chemotherapy for adult T-cell leukemia 22 months before visiting our department. Intraoral examination revealed an elastic hard mass measuring 35×30×15mm in the left lower premolar region. Blood biochemical examination was positive for anti-HTLV-I antibody. A thoracoabdominal CT scan revealed no other lesion. Incisional biopsy confirmed the histopathological diagnosis of T-cell lymphoma, diffuse pleomorphic type. Although chemotherapy and radiotherapy were conducted, the patient died five months after the first treatment.