Abstract
Fifty-seven patients with SCC of the lower alveolus and gingiva, treated by surgery after preoperative therapy, were studied, to clarify the correlation between regression rate and histological effects of preoperative therapy, in soft tissue and in the mandible. The results were as follows: 1. cases with good clinical response to preoperative therapy, 75% or more of tumor regression rate tended to have good prognosis. 2. In cases with good clinical response, the histological effects of preoperative therapy on soft tissue tended to be good. 3. The histological findings after preoperative therapy in the mandible were almost the same as those in the soft tissue. 4. In the cases with invasive-type mandible absorption on X ray, viable cancer cells tended to be left in bone marrow after preoperative therapy.
