Abstract
This research was conducted to better understand the relationship between observations of tongue carcinoma using enhanced CT images and the effects of preoperative treatment. We created a comparative review of the effects of contrast images and preoperative treatment as well as histologic findings, using the enhanced CT images of 10 instances, of tongue squamous cell carcinoma after preoperative treatment and surgical removal of the primary site.
It was observed from the enhanced CT images that there was a tendency for the more intense the contrast effect before the preoperative treatment, the more effective the histologic treatment. In terms of histology, these cases had the tendencies of having stronger lymphocytic infiltration and more blood vessels. In a case where the preoperative treatment reduced the contrast effect, the reduction of lymphocytic infiltration and blood vessels, which was coincident with increased fibrous interstitial, was observed. In a case where the contrast effect intensified, an increase of granulation tissue with an abundant blood vessels was observed. These results showed that the enhanced CT images reflected an observation of interstitial tissues and suggested that the changes of the enhanced CT images as a result of the preoperative treatment reflected the histological change.