2002 Volume 14 Issue 2 Pages 53-61
Clinical examination was performed in 4 cases of malignant melanoma in the oral and maxillof acial region, in the Dapartment of Oral and Maxillof acial Surgery II, Okayama University Dental School. The patients consisted of 2 men and 2 women, of ages from 57 to 75. The tumor location was the lower gingiva in 1 patient, and the palate in 3. According to the criteria of the UICC (1997), 1 case was classified as stage I a, 1 as stage II, and 2 as stage III. All cases underwent surgical excision combined with chemotherapy, immunotherapy, hormonotherapy, or a combination of these modalities. Two cases died of local recurrence or regional lymph node or distant metastasis. Two cases had no evidence of local recurrence or distant metastasis after 14 years 11 months, and 3 years 8 months, respectively.
