A case of carcinoma of the tongue treated with a combination of intra-arterial infusion chemotherapy and radiotherapy

Abstract

In our hospital, a combination of intra-arterial infusion chemotherapy and radiotherapy has been performed to preserve functions and morphology in case of oral cancers. In this study, we report a case in which we performed the combined therapy without surgical therapy at the time of primary treatment, and a good clinical course has been observed up to date.
The patient was a 67-years-old male who had a 58×50 mm tumor of left tongue on thelef t side.
During hospitalization, we performed seldinger into the femoral artery, then performed chemotherapy with CBDCA (total dose 900 mg), and radiotherapy (Linac, total dose of irradiation : 40 Gy) .
After treatment, the tumor disappeared, and therapeutic effect was evaluated as complete response based on functional imaging diagnosis using positron emission tomography. The patient is under maintenance therapy, and no recurrence or metastasis have been observed during the 3 years since treatment.