A clinical study on treatment and prognosis of patients with squamous cell carcinoma of oral cavity

1. Local cure of those who undergo surgery

Abstract

A clinical study was made on the local status of 147 patients with oral squamous cell carcinoma who underwent surgery between 1999 and 2004. Local recurrence occurred in 10 patients (3/78 for tongue, 1/28 for mandibular gingiva, 1/16 for buccal mucosa, 1/9 for upper gingiva or hard palate, 2/7 for floor of the mouth, 0/9 for oropharynx, and 2/3 for central carcinoma of the mandible), and 2 patients finally died of local failure. The 5-year cumulative survival rate for 10 patients with local recurrence was low, being 40%, in contrast to 87.3% for 137 without local recurrence. These findings showed that most patients with oral cancer obtained local cure but the prognosis of those who had local recurrence was poor. The selection of operation methods at the initial therapy seemed to be important.