A case of double primary carcinomas originated from the submandibular gland and the lung

Abstract

Multiple primary tumors are increasing as a result of the increase of malignant tumors. Some cases are difficult to be distinguished from metastatic tumors.
A case of multiple primary carcinomas in the left side submandibular gland and the right side lung was reported. A 77 year-old man visited our department complaining of a painless swelling on the left side of the submandibular region. There was no swelling in the regional lymph nodes. X-ray examination revealed a tumorous lesion in the right side lung. Biopsy of the submandibular lesion was performed and histopathological diagnosis was mucoepidermoid carcinoma of submandibular gland. Biopsy of the lung tumor indicated the possibility that the tumor was metastasis from the salivary gland tumor. Under general anesthesia the tumor of submandibular gland was excised with the surrounding healthy tissues, and the submandibular region was immediately reconstructed with D-P flap and titanium plate. One month after the operation the lung tumor was excised and the D-P flap was ressected. Histopathological diagnosis of the lung tumor was poorly differentiated adenocarcinoma of the lung.
From the above this case was proved to be multiple primary carcinoma of the submandibular gland and the lung.