Abstract
Among 413 cases of primary squamous cell carcinoma of the oral and maxillofacial region in Oral Surgery Clinic of Saitama Cancer Center between 1975 and 1995, the carcinoma of the upper alveolus and gingiva (22 cases) and hard palate (8 cases) were evaluated clinicopathologically and compared with the carcinoma of the maxillary sinus (30 cases) .
The characteristics of the carcinoma of the upper alveolus and gingiva, and hard palate were as follows : Incidence was 7.9% of 413 cases of primary squamous cell carcinoma of the oral and maxillofacial region, especially low for carcinoma of the hard palate. As for sex, cases of carcinoma were predominantly female. As for the elderly, the mean age was about 70 years. Over half were 1 and 2 by T-classification, but only 36.7% were I and II by stage-classification. Histopathological findings revealed the same number of cases of I and II, all of which had a tendency to cornification, but no III by WHO-classification. The number of cases of types 2, 3, and 4C, but not 1 and 4D, were also almost the same by Yamamoto-Kohama Classification for mode of invasion. Combined therapy of irradiation, reduction surgery, and continuous intraarterial chemotherapy was mainly performed, and partly performed combined therapy of irradiation and reduction surgery using CO2 LASER. Cumulative survival rates of 3 and 5 years were both 78.3%.