Abstract
Sodium dodecyl sulfate (SDS), synthetic detergent is included in commercial dentifrice. SDS has protein denaturation action, and it is noxious for oral mucosa. Ecol dental herbyTM is a dentifrice manufactured from only natural plant materials without noxious compound. We evaluated the efficacy of Ecol dental herbyTM in 80 patients with xerostomia, glossodynia or dysgeusia. As a result, it had no effect on saliva flow rate, subjective and objective symptom of xerostomia and dysgeusia in use of 3 months. However, the pain of glossodynia was significantly improved. In addition, the adverse event was not found all over the periods of use at all. These results suggest that Ecol dental herbyTM might be effective for glossodynia.