Abstract
Promotion of appropriate use of antimicrobial agents is one of the most important problems in nosocomial infection control. The infection control team (ICT) at Showa University Dental Hospital started to use a notification policy for antimicrobial agents (fourth-generation cephalosporins, carbapenems and antimethcillin-resistant Staphylococcus aureus (MRSA) agnents from 2010. In this study, consumption of the antimicrobial agents and the trends of antimicrobial resistance were verified before and after the introduction of the notification policy, and the system was evaluated. Antimicrobial usage density (AUD) of ABPC and CEZ in 2011 was increased remarkable compared with that of in 2009. Total AUD of antimicrobial agents was almost same from 2009 to 2011. Total expenditure of antimicrobial agents had been decreased each year. MRSA, multidrug-resistant Pseudomonas aeruginosa and extended-spectrum beta-lactamase producing enterobacteria were not detected. Therefore, positive intervention by ICT is important for promotion of appropriate use of antimicrobial agents, prevent to increase in drug resistant bacteria and contribute for economic impact on the hospital.
