Abstract
Clincal evaluation of sulbactam/cefoperazone was carried out in 10 cases of osteitis of jaw and in 8cases of cellulitis.
1. The clinical efficacy rate was 77.8 % according to the evaluation score on the 3rd day of treatment, and 72.2 % by the doctor's judgement.
2. Of 14 patients who failed to respond to previous antibiotic treatments, 11 (78.6 %) were effectively treated by SBT/CPZ.
3. MICs of SBT/CPZ against aerobic and anaerobic bacteria were low, and SBT/CPZ resistant strains were not found.
4. As for side effects, they were moderate-some diarrhea appeared in one case. Abnormal findings in the hepatic function test were noted in 3 cases, but the changes were not clinically important.
5. These results indicate the usefulness of sulbactam/cefoperazone in the treatment of odontogenic infections.
