ORAL THERAPEUTICS AND PHARMACOLOGY
Online ISSN : 1884-4928
Print ISSN : 0288-1012
ISSN-L : 0288-1012
The two cases of acute odontogenic infections treated with combination therapy of clindamycin phosphate with ceftazidime
YASUMASA SAIKIKIYOMASA NAKAGAWASHIGEHIRO KUMAGAIETSUHIDE YAMAMOTO
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1994 Volume 13 Issue 1 Pages 16-21

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Abstract
A combination therapy of clindamycin phosphate (CLDM) with ceftazidime (CAZ) was used in 2 cases of acute odontogenic infections. In the first case, 2 isolated bacteria strains were Peptostreptococcus micros and β lactamase-producing Prevotella oralis. In the second case, 4 isolated strains were Streptococcus constellatus, P. micros, Porphyromonas gingivalis and, β lactamase-producing Bacteroides capillosus. β lactamase-producing bacteria in two cases were highly sensitive to combination therapy of CLDM with CAZ. In conclusion, combination therapy of CLDM with CAZ is useful for speeding recovery and effective in oral suppurative mixed infections with β lactamase-producing bacteria.
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