Abstract
A single oral dose of 100 mg of cefdinir (CFDN) was administrated to 107 patients and the effusion concentration of CFDN at the wound site after exodontia was determined. When the concentration was set at 0.1 μg/ml (MIC90) as a chemoprophylactic target level, all cases had obtained a higher corcentration than the target level during 60-490 minutes after the administration.
From these results, it is indicated that CFDN is a useful agent for prophylaxis and treatment of odontogenic infections.
