Abstract
The antibacterial activity of flavonoid phytoalexin, 5, 7, 2', 4'-tetrahydroxy-8-lavandulylflavanone (sophoraflavanone G) isolated from the roots of Sophora exigua, against periodontopathic and opportunistic bacteria was investigated, Sophoraflavanone G completely inhibited the growth of Porphyromonas, Prevotella, Actinobacillus, Capnocytophaga, Fusobacterium and Eubacterium at <0.8-25.0 μg/ml. Gram-positive staphylococci and streptococci were also inhibited at 1.56-3.13 pg/ml. The present antibacterial phytochemical would be a potent compound for the prevention of oral infections.
