Concomitant use and administration to the aged of new quinolone agents in 9 national university dental hospitals in Japan

Abstract

After our previous report, the concomitant use and the administration to aged patients of new quinolon agents (NQs) at 9 hospitals of 11 national university dental hospitals in Japan were surveyed.
Among the prescriptions received in 9 hospital pharmacies (36, 000 sheets/2 months), those containing NQs were only 666 (1.85%) .
As for these 666 prescriptions, the cases in which careful administration of NQs with other medicines is recommended was 54%.
Undesirable concomitant use of NQs with nonsteroidal anti-inflamatory drugs were frequently observed, but combined use of NQs with antacid such as aluminium salt or magnesium salt were few.
The rate of prescriptions for aged patients in whom careful administration of NQs is demanded was 19.5%. The mean age of the oldest patient in each hospital was 75.7 and the oldest was 83. In addition, the rate of prescriptions containing one, two, and three doubtful points were 25.2, 9, and 1.1%, respectively.