Clinical isolates from odontogenic infections and their antibiotic susceptibilities

JIRO SASAKI; TAKEFUMI MORIHANA; MASATAKA UEMATSU; HIROSHI TAKAI; KATSUYOSHI IKESHIMA; KAZUO SHIIKI; TETSURO HASHIMOTO; ISSHU KAWANISHI; YOSHIKUNI SANGU; TAKAHO KUWAZAWA; YASUNOBU UCHIDA; YOSHIHIRO NARITA; YOSHINOBU SASAO; YOSHIO HISANO; TAZUKO SATOH; ATSUSHI NOMURA; KEN-ICHI MICHI; KOHSUKE OHNO; TAKESHI SHIOTA; KATSUNORI ISHIBASHI; KOH-ICHI ASADA; KAZUNORI OHTSUBO; TAKANORI HATTORI; NORIAKI IKEDA; SUSUMU IIDA; TADASHI YAMAMOTO; KEIKICHI SHIMADA; KOH-ICHI NAKANISHI; TAMOTSU OKUSHA; KOH-ICHI DEGUCHI

doi:10.11263/jsotp1982.5.87

JIRO SASAKI, TAKEFUMI MORIHANA, MASATAKA UEMATSU, HIROSHI TAKAI, KATSUYOSHI IKESHIMA, KAZUO SHIIKI, TETSURO HASHIMOTO, ISSHU KAWANISHI, YOSHIKUNI SANGU, TAKAHO KUWAZAWA, YASUNOBU UCHIDA, YOSHIHIRO NARITA, YOSHINOBU SASAO, YOSHIO HISANO, TAZUKO SATOH, ATSUSHI NOMURA, KEN-ICHI MICHI, KOHSUKE OHNO, TAKESHI SHIOTA, KATSUNORI ISHIBASHI, KOH-ICHI ASADA, KAZUNORI OHTSUBO, TAKANORI HATTORI, NORIAKI IKEDA, SUSUMU IIDA, TADASHI YAMAMOTO, KEIKICHI SHIMADA, KOH-ICHI NAKANISHI, TAMOTSU OKUSHA, KOH-ICHI DEGUCHI

Author information

JIRO SASAKI
Department of Oral Surgery, School of Medicine, Tokai University
TAKEFUMI MORIHANA
Department of Oral Surgery, School of Medicine, Tokai University
MASATAKA UEMATSU
Department of Oral Surgery, School of Medicine, Tokai University
HIROSHI TAKAI
First Department of Oro-Maxillo-Facial Surgery, Tohoku Dental University
KATSUYOSHI IKESHIMA
First Department of Oro-Maxillo-Facial Surgery, Tohoku Dental University
KAZUO SHIIKI
Department of Dentistry and Oral Surgery, Iwaki Kyoritsu General Hospital
TETSURO HASHIMOTO
Department of Dentistry and Oral Surgery, Ashikaga Sekijuji Hospital
ISSHU KAWANISHI
Department of Oral Surgery, Tokyo Women's Medical College
YOSHIKUNI SANGU
Department of Oral Surgery, Tokyo Women's Medical College
TAKAHO KUWAZAWA
Department of Oral Surgery, Tokyo Women's Medical College
YASUNOBU UCHIDA
Department of Oral Surgery, Tokyo Medical College
YOSHIHIRO NARITA
Department of Oral Surgery, Tokyo Medical College
YOSHINOBU SASAO
Department of Oral Surgery, Tokyo Medical College
YOSHIO HISANO
Department of Oral and Maxillofacial Surgery I, School of Dentistry at Tokyo, The Nippon Dental University
TAZUKO SATOH
Department of Oral and Maxillofacial Surgery I, School of Dentistry at Tokyo, The Nippon Dental University
ATSUSHI NOMURA
Department of Oral and Maxillofacial Surgery I, School of Dentistry at Tokyo, The Nippon Dental University
KEN-ICHI MICHI
First Department of Oral and Maxillofacial Surgery, School of Dentistry, Showa University
KOHSUKE OHNO
First Department of Oral and Maxillofacial Surgery, School of Dentistry, Showa University
TAKESHI SHIOTA
First Department of Oral and Maxillofacial Surgery, School of Dentistry, Showa University
KATSUNORI ISHIBASHI
Second Department of Oral and Maxillofacial Surgery, School of Dental Medicine, Tsurumi University
KOH-ICHI ASADA
Second Department of Oral and Maxillofacial Surgery, School of Dental Medicine, Tsurumi University
KAZUNORI OHTSUBO
Second Department of Oral and Maxillofacial Surgery, School of Dental Medicine, Tsurumi University
TAKANORI HATTORI
Second Department of Oral and Maxillofacial Surgery, School of Dentistry, Aichi-Gakuin University
NORIAKI IKEDA
Second Department of Oral and Maxillofacial Surgery, School of Dentistry, Aichi-Gakuin University
SUSUMU IIDA
Second Department of Oral and Maxillofacial Surgery, School of Dentistry, Aichi-Gakuin University
TADASHI YAMAMOTO
Department of Dental and Oral Surgery, Toyohashi Municipal Hospital
KEIKICHI SHIMADA
Department of Oral and Maxillofacial Surgery, School of Medicine, Kobe University
KOH-ICHI NAKANISHI
Department of Oral and Maxillofacial Surgery, School of Medicine, Kobe University
TAMOTSU OKUSHA
Department of Oral and Maxillofacial Surgery, School of Medicine, Kobe University
KOH-ICHI DEGUCHI
Laboratory Section, Tokyo Clinical Research Center

Keywords: Clinical isolated bacteria, Odontogenic infections, Antibiotic susceptibilities, New quinolones

JOURNAL FREE ACCESS

1986 Volume 5 Issue 2 Pages 87-96

DOI https://doi.org/10.11263/jsotp1982.5.87

Details

Abstract

Bacteriological studies were carried out in the field of oral and maxillofacial surgery. One hundred and ninety eight strains were isolated from the pus of closed abscesses in 88 patients with odontogenic infections. Their susceptibilities to Ofloxacin (OFLX), Ciprofloxacin (CPFX), Ampicillin (ABPC), Erythromycin (EM) and Cephalexin (CEX) weredetermined. The results obtained were as follows:
1) Peptostreptococcus spp., α-Streptococcus and anaerobic streptococci were isolated in high frequency and these 3 strains occupied 67.7% of all the strains.
2) The isolated percentage of aerobes and anaerobes was 42.4% and 57.6%, respectively, and anaerobes were isolated from 78 out of 88 patients. These results suggest the important role of anaerobes in odontogenic infections.
3) As a whole, ABPC exhibited strong antibacterial activities. OFLX and CPFX inhibited the growth of almost all the strains at a concentration of less than 6.25μg/ml. Though EM showed good antibacterial activity, some highly resistant Peptostreptococcus spp. and anaerobic streptococci were isolated. CEX had lower activity compared with the other 4 drugs.

Corresponding author

Register with J-STAGE for free!