Blood level of exodontia wound after oral administration of Lenampicillin (LAPC)

Abstract

Oral dose of 500 mg lenampicillin was administered before exodontia in 250 patients a sum total of 284 times.
Drug concentration as ampicillin in the blood from the exodontia wound was measured.
MIC 90% of the isolates from odontogenic infection including Oral Streptococci was 0.39μg/ml.
This antimicrobial agent valued≥0.39μg/ml 83 cases out of 88 cases (94%) between 60 minutes and 135 minutes after peroral administration.