Bacteriological evaluation of organisms isolated from a collaborative clinical study of Cefteram pivoxil (CFTM-PI)

Abstract

Bacteriological studies were carried out in the field of oral and maxillofacial surgery. The total number of isolated organisms were 164 species. The results were as follows.
1. Gram-positive bacteria were isolated from the oral infections using high frequency.
2. Oral streptococci were the major isolates and S. anginosus, S. interntedius and S. constellatus were isolated individually.
3. The anaerobes were isolated mainly from mixed infections.
Especially anaerobic gram-negative bacteria tended to be isolatded from the osteitis of jaw.
4. The MIC for 80% of organisms of CFTM, CCL and ABPC were 0.05, 1.56 and 0.025μg/ml against Oral Streptococci.
5. Judging from Cmax/MIC and the above MIC, CFTM and ABPC were acceptable for first choice.