Abstract
Recent early intervention studies with inhaled corticosteroids (ICS) for high risk infants with wheeze failed to show that ICS can alter natural history of asthma in childhood. Disappointment on the results, however, has provoked various perspectives on the potentials and limitations of ICS, and future strategies to cure asthma. In this review, the current understandings of ICS for asthma will be summarized and prospects will be discussed.