Abstract
Studies of the natural history of asthma have demonstrated that 30-50% of children with asthma experience remission, and that approximately 30% of them relapse later. Factors contributing to persistence or relapse of asthma are following; delayed use of inhaled steroid, airway remodeling, allergic states, genetic factors, and environments. The most promising strategy for inducing remission and keeping their remission states longer could be a multi-interventional approach focusing on these factors. However, there have been few evidences in this context. Further prospective long-term studies will be needed.
