Abstract
Reports of efficacy on specific oral tolerance induction are increasing from the specialized institutes in Europe and USA, but there is no standardized method of the oral tolerance induction therapy for persistent food allergy. We think that the indication of the therapy is for the persistent food allergy patients (>6y) with the most severe symptoms so-called “anaphylaxis”. In our hospita1, we doubled the quantity of intakes twice a day over 6-9 days from the equivalent dose of the threshold in admission during the rapid induction phase. We here discuss the indication and methodology from our own experience and the reports on oral tolerance induction for possible standardization of the therapy.